Natural History of Experimental Arterial Chronic Total Occlusions

Natural history of experimental arterial chronic total occlusions.

OBJECTIVES We sought to perform the first systematic study of the natural history of chronic total arterial occlusions (CTOs) in an experimental model. BACKGROUND Angioplasty of CTOs has low success rates. The structural and perfusion changes during CTO maturation, which may adversely affect angioplasty outcome, have not been systematically studied. METHODS Occlusions were created in 63 rab...

Treatment of chronic arterial occlusions with streptokinase.

Intracoronary imaging in chronic total occlusions

Chronic total occlusion (CTO) intervention constitutes approximately 10–20% of all angioplasty procedures at selected centers. Benefits of CTO revascularization, in addition to relief of angina, include improvement of left ventricular function, reduced risk of major adverse cardiac events and potentially increased survival. Although several techniques, devices and guidewires have been developed...

Antegrade Techniques for Chronic Total Occlusions

By convention, a total obstruction of the coronary artery with no flow at the occluded segment that has been present for at least 3 months is termed as chronic total occlusion or CTO. This is to be distinguished from a sudden occlusion of the coronary artery lumen by a thrombus during an acute myocardial infarction. Percutaneous coronary intervention (PCI) of CTO is increasingly being performed...

Percutaneous Coronary Intervention for Chronic Total Occlusions

I mpasses are common in everyday life. When they occur in coronary arteries as chronic total occlusions (CTOs), they may be difficult to treat. Successful treatment of CTOs sometimes requires a nonconformist approach based on “negative thinking,” which is described in philosophical circles as the mindset that “negates” the possibility of failure and replaces it with the potentiality of success ...